Knocked Up is one of the most well structured comedies I've seen in a while. A smart, professional woman gives in to a drunken night of sex with a man who could not be less of a match for her. The surprise pregnancy could be tragic, but the tone of the characters and their willingness to change, for each other, and the baby, sets up an interesting situation. It doesn't come easy, it's pretty realistic. Events take a predictable course, but the dialogue and delivery held the key to comedy for me. In the tradition of Wedding Crashers and The 40 Year Old Virgin, the goofy friends and caring family are funny, off color, and endearing. This film exhibits a firm grasp of the use of the word f**k for comedic effect and realism, well done. And who would have thought a rant from Ryan Seacrest would be funny?
PS (Stay for the credits, they show baby pictures of the cast and crew .... very cute!)